Hu-Cytokines

Recombinant Human FGF-7

Cat No. Size Price Add Cart
HST-F7-0010 10ug $ 213.00 Add Cart
HST-F7-0100 100ug $ 1491.00 Add Cart
HST-F7-1000 1000ug $ 5325.00 Add Cart

Product Specifications

•      Expression of Human Proteins in Human Cells
•      Extreme low Endotoxin
•      High Purity
•      Animal Free and Xeno Free
•      Tag Free

 

Source: Human cells derived
Structure: Glycosylated homodimer
Purity: >95% by SDS-PAGE
Endotoxin Level: <0.5EU/ug
Molecular Weight: 17-30kDa
Formulation: Lyophilized from a 0.2μm filtered solution in PBS without carrier protein

 

Activity Assay

The activity was measured by its ability to stimulate the proliferation of 4MBr-5 cells (monkey epithelial cell line).

 

Reconstitution

Briefly centrifuge the vial before opening. It is recommended to reconstitute the protein in sterile PBS containing 0.1% endotoxin-free recombinant human serum albumin.

 

Stability & Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. In general: 12 months from date of receipt, -20 to -80°C as supplied. 1 month, 2 to 8°C under sterile conditions after reconstitution. 3 months, -20 to -80°C under sterile conditions after reconstitution.

 

Protein Description

FGF-7 (KGF) is a member of the fibroblast growth factor family. FGF-7 is expressed in mesenchymal origin cells. FGF-7 plays an  important  role  in the regulation of embryonic development, cell proliferation and cell differentiation. FGF-7 is required for normal branching morphogenesis, growth    factor  active   on   keratinocytes.   FGF- 7 is possible major paracrine effector of normal epithelial cell proliferation.

References

Finch PW, et al. (1989) Science 245,752-755.
Aaronson SA, et al. (1991) Ann. N. Y. Acad. Sci.638, 62-77. Werner S, et al. (2007) J. Invest. Dermatol. 127,998.
Ann. N. Y. Acad. Sci.638, 62-77. Werner S, et al. (2007) J. Invest. Dermatol. 127,998