Recombinant Human IL-12

Cat No. Size Price Add Cart
HCT-I12-0010 10ug $ 205.00 Add Cart
HCT-I12-0100 100ug $ 1765.00 Add Cart
HCT-I12-1000 1000ug $ 6350.00 Add Cart

Product Specifications

•      Expression of Human Proteins in Human Cells

•      Extreme low Endotoxin

•      High Purity

•      Animal Free and Xeno Free

•      Tag Free


Source: Human cells derived

Structure: Glycosylated heterodimer

Purity: >95% by SDS-PAGE

Endotoxin Level: <0.5EU/ug

Molecular Weight:57kDa

Formulation: Lyophilized from a 0.2μm filtered solution in PBS without carrier protein


Activity Assay

The activity was measured by its ability to stimulate the proliferation of PHA transformed human peripheral blood lymphoblast



Briefly centrifuge the vial before opening. It is recommended to reconstitute the protein in sterile PBS containing 0.1% endotoxin-free recombinant human serum albumin.


Stability & Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. In general: 12 months from date of receipt, -20 to -80°C as supplied. 1 month, 2 to 8°C under sterile conditions after reconstitution. 3 months, -20 to -80°C under sterile conditions after reconstitution.


Protein Description

IL-12 is a disulfide-linked heterodimeric protein (p70), composed of two subunits, p35 and p40, which are encoded by two different genes. IL-12 is predominantly produced by macrophages and B lymphocytes. IL-12 functions as a growth factor for activated T and NK cells, enhences the lytic activity of NK/lymphokine activated killer cells, and stimulates the production of IFN-γ by resting PBMC.


Oppmann B,et al. (2000) Immunity 13:715-725.

Gubler U, et al. (1991) Proc. Natl. Acad. Sci. 8, 4143-4147.