Hu-Cytokines

Recombinant Human GM-CSF

Cat No. Size Price Add Cart
HHM-GM-0010 10ug $ 205.00 Add Cart
HHM-GM-0100 100ug $ 1435.00 Add Cart
HHM-GM-1000 1000ug $ 3245.00 Add Cart

Product Specifications

•      Expression of Human Proteins in Human Cells

•      Extreme low Endotoxin

•      High Purity

•      Animal Free and Xeno Free

•      Tag Free

 

Source: Human cells derived

Structure: Glycosylated monomer

Purity: >95% by SDS-PAGE

Endotoxin Level: <0.5EU/ug

Molecular Weight: 15-36kDa

Formulation: Lyophilized from a 0.2μm filtered solution in PBS without carrier protein

 

Activity Assay

The activity was measured by its ability to stimulate the proliferation of human TF-1 cells (human erythroleukemic indicator cell line).

 

Reconstitution

Briefly centrifuge the vial before opening. It is recommended to reconstitute the protein in sterile PBS containing 0.1% endotoxin-free recombinant human serum albumin.

 

Stability & Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. In general: 12 months from date of receipt, -20 to -80°C as supplied. 1 month, 2 to 8°C under sterile conditions after reconstitution. 3 months, -20 to -80°C under sterile conditions after reconstitution.

 

Protein Description

Granulocyte macrophage colony stimulating factor (GM-CSF) is a cytokine  initially  characterized by its ability to induce colonies of granulocytes and macrophages from myeloid progenitor cells. It is produced in endothelial cells, monocytes, fibroblasts and T lymphocytes. GM-CSF stimulates the growth and differentiation of hematopoietic precursor cells from various lineages, including granulocytes, macrophages, eosinophils and erythrocytes.

References

Wong GG, et al. (1985) Science 228,810-815.

Barreda DR, et al. (2004) Dev. Comp. Immunol.28, 509.

Volmar CH, et al. (2008) Cytokine 42, 336-344.