Recombinant Human NGF-β
|Cat No.||Size||Price||Add Cart|
|HST-N-0010||10ug||$ 105.00||Add Cart|
|HST-N-0100||100ug||$ 306.00||Add Cart|
|HST-N-1000||1000ug||$ 1650.00||Add Cart|
• Expression of Human Proteins in Human Cells
• Extreme low Endotoxin
• High Purity
• Animal Free and Xeno Free
• Tag Free
Source: Human cells derived
Structure: Glycosylated monomer
Purity: >95% by SDS-PAGE
Endotoxin Level: <0.5EU/ug
Molecular Weight: 13kDa
Formulation: Lyophilized from a 0.2μm filtered solution in PBS without carrier protein
The activity was measured by its ability to stimulate the proliferation of human TF-1 cells (human erythroleukemic indicator cell line).
Briefly centrifuge the vial before opening. It is recommended to reconstitute the protein in sterile PBS containing 0.1% endotoxin-free recombinant human serum albumin.
Stability & Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. In general: 12 months from date of receipt, -20 to -80°C as supplied. 1 month, 2 to 8°C under sterile conditions after reconstitution. 3 months, -20 to -80°C under sterile conditions after reconstitution.
Nerve growth factors (NGFs ) is composed of three noncovalently linked subunits, α, β, and γ, while the β subunit, called NGF-β exhibits all the biological activities ascribed to NGF. Recombinant human NGF-β is a homodimer of two 120 amino acid polypeptides. NGF-β is important for the development and maintenance of the sympathetic and sensory nervous systems. NGF-β is a well characterized neurotropic protein that plays a critical role in the development of sympathetic and some sensory neurons in the peripheral nervous system. In addition, NGF-β can also act in the central nervous system as a trophic factor for basal forebrain cholinergic neurons. NGF-β has also been shown to have biological effects on non- neuronal tissues.
Wijeyewickrema LC, et al. (2010) J. Biol. Chem. 285, 11793-11799.
Cirulli F, et al. (2009) Front. Neuroendo. 30, 379-395.