Recombinant Human OSM
|Cat No.||Size||Price||Add Cart|
|HST-O-0010||10ug||$ 185.00||Add Cart|
|HST-O-0100||100ug||$ 1025.00||Add Cart|
|HST-O-1000||1000ug||$ 3685.00||Add Cart|
• Expression of Human Proteins in Human Cells
• Extreme low Endotoxin
• High Purity
• Animal Free and Xeno Free
• Tag Free
Source: Human cells derived
Structure: Glycosylated monomer
Purity: >95% by SDS-PAGE
Endotoxin Level: <0.5EU/ug
Molecular Weight: 30kDa
Formulation: Lyophilized from a 0.2μm filtered solution in PBS without carrier protein
The activity was measured by its ability to stimulate the proliferation of human TF-1 cells (human erythroleukemic indicator cell line).
Briefly centrifuge the vial before opening. It is recommended to reconstitute the protein in sterile PBS containing 0.1% endotoxin-free recombinant human serum albumin.
Stability & Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. In general: 12 months from date of receipt, -20 to -80°C as supplied. 1 month, 2 to 8°C under sterile conditions after reconstitution. 3 months, -20 to -80°C under sterile conditions after reconstitution.
Oncostatin M (OSM) is a 30 kDa secreted cytokine belonging to the Interleukin 6 family. OSM inhibits the proliferation of a number of tumor cell lines. It also stimulates proliferation of AIDS-KS cells. It regulates cytokine production, including IL-6, G-CSF and GM-CSF from endothelial cells. OSM plays crucial roles in inflammation, neuroprotection, hematopoiesis, metabolism and development.
Malik N, et al. (1989) Mol. Cell. Biol. 9, 2847-2853.
Rose TM, et al. (1991) Proc. Natl. Acad. Sci. U.S.A.88,8641-8645.