Recombinant Human BMP-7
|Cat No.||Size||Price||Add Cart|
|HST-B7-0010||10ug||$ 208.00||Add Cart|
|HST-B7-0100||100ug||$ 1491.00||Add Cart|
|HST-B7-1000||1000ug||$ 7455.00||Add Cart|
• Expression of Human Proteins in Human Cells
• Extreme low Endotoxin
• High Purity
• Animal Free and Xeno Free
• Tag Free
Source: Human cells derived
Structure: Glycosylated homodimer
Purity: >95% by SDS-PAGE
Endotoxin Level: <0.5EU/ug
Molecular Weight: 30-38kDa
Formulation: Lyophilized from a 0.2μm filtered solution in PBS without carrier protein
The activity was measured by its ability to induce alkaline phosphatase production in the ATDC-5 cell line (Mouse chondrogenic cell line).
Briefly centrifuge the vial before opening. It is recommended to reconstitute the protein in sterile
4 mM HCl containing at least 0.1% human or bovine serum albumin.
Stability & Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. In general: 12 months from date of receipt, -20 to -80°C as supplied. 1 month, 2 to 8°C under sterile conditions after reconstitution. 3 months, -20 to -80°C under sterile conditions after reconstitution.
Bone morphogenetic protein 7 (BMP-7), also known as osteogenic protein 1 (OP1) is a member of transforming growth factor β family that includes more than 20 structurally related bone growth factors. BMP-7 plays an important role in cartilage and bone formation. It also plays a role in calcium regulation and kidney development. Mature human BMP-7 is usually a homodimer consisting of two antiparallel monomers of 139 amino acids. Dimerization is facilitated by a disulfide bridge formed between the monomer, which contains three intrachain disulfide bridges arranged in a cystine knot motif.
Wang RN, et al. (2014)Genes& Diseases 1,87e105. Chen D, et al. (2004)Growth Factors 22:233.
Celeste AJ, et al. (1990)Proc. Natl. Acad. Sci.U.S.A. 87,9843-9847.