Non-HuCytokines

Recombinant Human FGF-7 (KGF)

Cat No. Size Price Add Cart
EST-KF-0010 10ug $ 195.00 Add Cart
EST-KF-0100 100ug $ 1025.00 Add Cart
EST-KF-1000 1000ug $ 5358.00 Add Cart

Source: E. coli derived
Structure: Monomer
Purity: >95% by SDS-PAGE
Endotoxin Level: <1EU/ug
Molecular Weight: 19kDa
Formulation: Lyophilized from a 0.2μm filtered solution in PBS without carrier protein

Activity Assay

The activity was measured by its ability to stimulate   the proliferation of 4MBr-5 cells (monkey epithelial cell line).

Reconstitution

Briefly centrifuge the vial before opening. It is recommended to reconstitute the protein in sterile PBS containing 0.1% endotoxin-free recombinant human serum albumin.

Stability & Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. In general: 12 months from date of receipt, -20 to -80°C as supplied. 1 month, 2 to 8°C under sterile conditions after reconstitution. 3 months, -20 to -80°C under sterile conditions after reconstitution.

Protein Description

FGF­7 (KGF) is a member of the fibroblast growth factor family. FGF-7 is expressed in mesenchymal origin cells. FGF-7 is a mitogen factor specific for epithelial cells and keratinocytes. FGF-7 plays a role in kidney and lung development, as well as in angiogenesis and wound healing. FGF­7 also plays an important role in the regulation of embryonic development, cell proliferation and cell differentiation. FGF­7 is possible major paracrine effector of normal epithelial cell proliferation.

References

Finch PW, et al. (1989) Science 245,752-755
Aaronson SA, et al. (1991) Ann. N. Y. Acad. Sci. 638, 62-77.
Werner S, et al (2007) J. Invest. Dermatol. 127,998.