Non-HuCytokines

Recombinant Human IFN-γ

Cat No. Size Price Add Cart
EST-IFg-0010 10ug $ 50.00 Add Cart
EST-IFg-0100 100ug $ 165.00 Add Cart
EST-IFg-1000 1000ug $ 1085.00 Add Cart

Source: E. coli derived
Structure: Noncovalently linked homodimer
Purity: >95% by SDS-PAGE
Endotoxin Level: <1EU/ug
Molecular Weight: 16.8 kDa
Formulation: Lyophilized from a 0.2μm filtered solution in PBS without carrier protein

 

Activity Assay

Determined by its ability to induce apoptosis in HeLa cells.
 

Reconstitution

Briefly centrifuge the vial before opening. It is recommended to reconstitute the protein in sterile PBS containing 0.1% endotoxin-free recombinant human serum albumin.

Stability & Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. In general: 12 months from date of receipt, -20 to -80°C as supplied. 1 month, 2 to 8°C under sterile conditions after reconstitution. 3 months, -20 to -80°C under sterile conditions after reconstitution.

Protein Description

IFN-γ is an acid-labile interferon produced by Th1, cytotoxic T cells, NKT cells and NK cells. Interferon gamma (IFNγ) is a dimerized soluble cytokine that is the type II class of interferons.IFN-γ signaling in antigen-presenting cells, and antigenrecognizing B and T lymphocytes, regulates the antigen-specific phases of the immune response. IFNγ is critical for innate and adaptive immunity against viral, protozoal, bacterial infections. It also exhibits antiviral, antiproliferative, and apoptotic effects. IFNγ is particularly suitable for human CIK activation along with IL-2.

References

Gray PW, et al. (1982)Nature 298 (5877): 859-63.
Jiang J, et al. (2013) J Transl Med 11:83.
Lin FC, et al. (2014)Cytokine Growth Factor Rev 25(4):369-76.