Recombinant Human IFN-γ
|Cat No.||Size||Price||Add Cart|
|EST-IFg-0010||10ug||$ 50.00||Add Cart|
|EST-IFg-0100||100ug||$ 165.00||Add Cart|
|EST-IFg-1000||1000ug||$ 1085.00||Add Cart|
Source: E. coli derived
Structure: Noncovalently linked homodimer
Purity: >95% by SDS-PAGE
Endotoxin Level: <1EU/ug
Molecular Weight: 16.8 kDa
Formulation: Lyophilized from a 0.2μm filtered solution in PBS without carrier protein
Determined by its ability to induce apoptosis in HeLa cells.
Briefly centrifuge the vial before opening. It is recommended to reconstitute the protein in sterile PBS containing 0.1% endotoxin-free recombinant human serum albumin.
Stability & Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. In general: 12 months from date of receipt, -20 to -80°C as supplied. 1 month, 2 to 8°C under sterile conditions after reconstitution. 3 months, -20 to -80°C under sterile conditions after reconstitution.
IFN-γ is an acid-labile interferon produced by Th1, cytotoxic T cells, NKT cells and NK cells. Interferon gamma (IFNγ) is a dimerized soluble cytokine that is the type II class of interferons.IFN-γ signaling in antigen-presenting cells, and antigenrecognizing B and T lymphocytes, regulates the antigen-specific phases of the immune response. IFNγ is critical for innate and adaptive immunity against viral, protozoal, bacterial infections. It also exhibits antiviral, antiproliferative, and apoptotic effects. IFNγ is particularly suitable for human CIK activation along with IL-2.
Gray PW, et al. (1982)Nature 298 (5877): 859-63.
Jiang J, et al. (2013) J Transl Med 11:83.
Lin FC, et al. (2014)Cytokine Growth Factor Rev 25(4):369-76.