Recombinant Human TGF-β2

Cat No. Size Price Add Cart
HST-B2-0010 10ug $ 185.00 Add Cart
HST-B2-0100 100ug $ 1020.00 Add Cart
HST-B2-1000 1000ug $ 5058.00 Add Cart

Product Specifications

•      Expression of Human Proteins in Human Cells
•      Extreme low Endotoxin
•      High Purity
•      Animal Free and Xeno Free
•      Tag Free
Source: Human cells derived
Structure: Non-glycosylated  homodimer
Purity: >95% by SDS-PAGE
Endotoxin Level: <0.5EU/ug
Molecular Weight: 13kDa and 25kDa in reduced and Non-reduced SDS-PAGE respectively.
Formulation: Lyophilized from a 0.2μm filtered solution in 50mM NaAOC PH4.0 without carrier protein


Activity Assay

The activity was measured by its ability to inhibit the IL-4 induced proliferation in mouse HT-2 cells (BALB/c spleen activated by sheep erythrocytes in the presence of IL-2).


Briefly  centrifuge  the  vial  before  opening.  It  is recommended to reconstitute the protein in sterile 4 mM  HCl  containing  at  least  0.1%  human  or bovine serum albumin.


Stability & Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. In general: 12 months from date of receipt, -20 to -80°C as supplied. 1 month, 2 to 8°C under sterile conditions after reconstitution. 3 months, -20 to -80°C under sterile conditions after reconstitution.


Protein Description

Transforming growth factor beta 2 (TGF-β2) is one of three closely related mammalian members of the large TGFβ superfamily, TGF-β1, β2, and β3, signal through the same receptor and elicit similar biological responses.  TGF-β2 is expressed in keratinocytes, granulosa cells, astrocytes, osteoblasts, mammary cells, and various cancer cells. TGF-β2 is secreted and complexed with two other proteins, LAP and TGFBP, and requires proteolytic cleavage to be active. Human TGF-β2 is a secreted, homodimer linked by intermolecular disulfide bonds that plays a role in many cellular processes,including embryogenesis and angiostasis. TGF-β2 also plays an extensive role in prenatal development.


Derynck R, et al. (1985) Nature 316,701-705.
Sporn MBet al. (2006) Cytokine Growth Factor Rev. 17:3.
Ugo Ripamonti U, et al.(2016)Front. Physiol., 08,396.
Massagué J (2012)Nature Reviews Molecular Cell Biology. 13 (10): 616.