Recombinant Human TGF-β2
|Cat No.||Size||Price||Add Cart|
|HST-B2-0010||10ug||$ 185.00||Add Cart|
|HST-B2-0100||100ug||$ 1020.00||Add Cart|
|HST-B2-1000||1000ug||$ 5058.00||Add Cart|
The activity was measured by its ability to inhibit the IL-4 induced proliferation in mouse HT-2 cells (BALB/c spleen activated by sheep erythrocytes in the presence of IL-2).
Briefly centrifuge the vial before opening. It is recommended to reconstitute the protein in sterile 4 mM HCl containing at least 0.1% human or bovine serum albumin.
Stability & Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. In general: 12 months from date of receipt, -20 to -80°C as supplied. 1 month, 2 to 8°C under sterile conditions after reconstitution. 3 months, -20 to -80°C under sterile conditions after reconstitution.
Transforming growth factor beta 2 (TGF-β2) is one of three closely related mammalian members of the large TGFβ superfamily, TGF-β1, β2, and β3, signal through the same receptor and elicit similar biological responses. TGF-β2 is expressed in keratinocytes, granulosa cells, astrocytes, osteoblasts, mammary cells, and various cancer cells. TGF-β2 is secreted and complexed with two other proteins, LAP and TGFBP, and requires proteolytic cleavage to be active. Human TGF-β2 is a secreted, homodimer linked by intermolecular disulfide bonds that plays a role in many cellular processes,including embryogenesis and angiostasis. TGF-β2 also plays an extensive role in prenatal development.