Recombinant Human TGF-β1
|Cat No.||Size||Price||Add Cart|
|HST-TB1-0010||10ug||$ 185.00||Add Cart|
|HST-TB1-0100||100ug||$ 1020.00||Add Cart|
|HST-TB1-1000||1000ug||$ 5058.00||Add Cart|
The activity was measured by its ability to inhibit the IL-4 induced proliferation in mouse HT-2 cells (BALB/c spleen activated by sheep erythrocytes in the presence of IL-2).
Briefly centrifuge the vial before opening. It is recommended to reconstitute the protein in sterile 4 mM HCl containing at least 0.1% human or bovine serum albumin.
Stability & Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. In general: 12 months from date of receipt, -20 to -80°C as supplied. 1 month, 2 to 8°C under sterile conditions after reconstitution. 3 months, -20 to -80°C under sterile conditions after reconstitution.
Transforming growth factor beta 1(TGF-β1) is one of three closely related mammalian members of the large TGF-β superfamily, TGF-β1, β2, and β3, signal through the same receptor and elicit similar biological responses. TGF-β1 is the most abundant isoform secreted by almost every cell type. TGF-β1 is a multifunctional cytokine that controls proliferation, differentiation and other functions in many cell types. Many cells synthesize TGF-β1 and have specific receptors for it. TGF-β1 positively and negatively regulates many other growth factors. TGF-β1 plays an important role in bone remodeling as it is a potent stimulator of osteoblastic bone formation, causing chemotaxis, proliferation and differentiation in committed osteoblasts.