Growth Factors

Recombinant Human TGF-β1

Cat No. Size Price Add Cart
HST-TB1-0010 10ug $ 185.00 Add Cart
HST-TB1-0100 100ug $ 1020.00 Add Cart
HST-TB1-1000 1000ug $ 5058.00 Add Cart

Product Specifications

•      Expression of Human Proteins in Human Cells
•      Extreme low Endotoxin
•      High Purity
•      Animal Free and Xeno Free
•      Tag Free
Source: Human cells derived
Structure: Non-glycosylated  homodimer
Purity: >95% by SDS-PAGE
Endotoxin Level: <0.5EU/ug
Molecular Weight: 25kDa
Formulation: Lyophilized from a 0.2μm filtered solution in 10mM NaAOC without carrier protein

Activity Assay

The activity was measured by its ability to inhibit the IL-4 induced proliferation in mouse HT-2 cells (BALB/c spleen activated by sheep erythrocytes in the presence of IL-2).


Briefly  centrifuge  the  vial  before  opening.  It  is recommended to reconstitute the protein in sterile 4 mM  HCl  containing  at  least  0.1%  human  or bovine serum albumin.

Stability & Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. In general: 12 months from date of receipt, -20 to -80°C as supplied. 1 month, 2 to 8°C under sterile conditions after reconstitution. 3 months, -20 to -80°C under sterile conditions after reconstitution.

Protein Description

Transforming growth factor beta 1(TGF-β1) is one of three closely related mammalian members of the large TGF-β superfamily, TGF-β1, β2, and β3, signal through the same receptor and elicit similar biological responses. TGF-β1 is the most abundant isoform secreted by almost every cell type. TGF-β1 is a multifunctional cytokine that controls proliferation, differentiation and other functions in many cell types. Many cells synthesize TGF-β1 and have specific receptors for it. TGF-β1 positively and negatively regulates many other growth factors. TGF-β1 plays an important role in bone remodeling as it is a potent stimulator of osteoblastic bone formation, causing chemotaxis, proliferation and differentiation in committed osteoblasts.


Derynck R, et al. (1985) Nature 316,701-705.
Wah SM , (2006) Immunol. Rev. 213, 213.
Tsang M, et al. (1995) Cytokine 7,389