Recombinant Human IL-4
|Cat No.||Size||Price||Add Cart|
|HCT-I4-0010||10ug||$ 205.00||Add Cart|
|HCT-I4-0100||100ug||$ 1075.00||Add Cart|
|HCT-I4-1000||1000ug||$ 3245.00||Add Cart|
The activity was measured by its ability to stimulate the proliferation of human TF-1 cells (human erythroleukemic indicator cell line).
Briefly centrifuge the vial before opening. It is recommended to reconstitute the protein in sterile PBS containing 0.1% endotoxin-free recombinant human serum albumin.
Stability & Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. In general: 12 months from date of receipt, -20 to -80°C as supplied. 1 month, 2 to 8°C under sterile conditions after reconstitution. 3 months, -20 to -80°C under sterile conditions after reconstitution.
Interleukin 4 (IL-4) is a 14-19kDa glycosylated monomer, belongs to the IL-4 / IL-13 family. IL-4 is primarily expressed by Th2 biased CD4+ T cells, mast cells, basophils, and eosinophils. IL-4 is a pleiotropic cytokine that participates in at least several B-cell activation processes as well as of other cell types. It is a co-stimulator of DNA- synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes.