Growth Factors

Recombinant Human IL-3

Cat No. Size Price Add Cart
HCT-I3-0010 10ug $ 205.00 Add Cart
HCT-I3-0100 100ug $ 785.00 Add Cart
HCT-I3-1000 1000ug $ 3245.00 Add Cart

Product Specifications

•      Expression of Human Proteins in Human Cells
•      Extreme low Endotoxin
•      High Purity
•      Animal Free and Xeno Free
•      Tag Free
Source: Human cells derived
Structure: Glycosylated monomer
Purity: >95% by SDS-PAGE
Endotoxin Level: <0.5EU/ug
Molecular Weight: 19kDa
Formulation: Lyophilized from a 0.2μm filtered solution in PBS without carrier protein

Activity Assay

The activity was measured by its ability to stimulate the proliferation of human TF-1 cells (human erythroleukemic indicator cell line).


Briefly  centrifuge  the  vial  before  opening.  It  is recommended to reconstitute the protein in sterile PBS  containing  at  least  0.1%  human  or bovine serum albumin.

Stability & Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. In general: 12 months from date of receipt, -20 to -80°C as supplied. 1 month, 2 to 8°C under sterile conditions after reconstitution. 3 months, -20 to -80°C under sterile conditions after reconstitution.

Protein Description

Interleukin-3 (IL-3) is belongs to hematopoietic growth factors. It is a secreted protein. IL-3 can improve the body's natural response to disease as part of the immune system.  IL-3 stimulates the differentiation of multipotent hematopoietic stem cells into myeloid progenitor cells (as opposed to lymphoid progenitor cells where differentiation is stimulated by IL-7) as well as stimulates proliferation of all cells in the myeloid lineage (erythrocytes, megakaryocytes, granulocytes, monocytes, and dendritic cells) in conjunction with other cytokines, such as EPO, GM-CSF, TPO and IL-6. Additionally, IL-3 aids in embryo implantation and placental development, was found to be decreased both in pregnant women with antiphospholipid syndrome and in animal models of APS. IL-3 also participates in the response of the organism to various types of stress.


Yang YC, et al. (1986). Cell 47(1): 3-10.
Martinez-Moczygemba M, et al (2003). J. Allergy Clin. Immunol. 112 (4): 653–65.