Hematopoietic SCs

Recombinant Human SCF

Cat No. Size Price Add Cart
HHM-SF-0010 10ug $ 208.00 Add Cart
HHM-SF-0100 100ug $ 1725.00 Add Cart
HHM-SF-1000 1000ug $ 4235.00 Add Cart

Product Specifications

 

Source: Human cells derived
Structure: Glycosylated monomer
Purity: >95% by SDS-PAGE
Endotoxin Level: <0.5EU/ug
Molecular Weight: 35-45kDa
Formulation: Lyophilized from a 0.2μm filtered solution in PBS without carrier protein

 

Activity Assay

The specific activity was determined by the dose- dependent simulation of the proliferation of human TF-1 cells (human erythroleukemic indicator cell line).

 

Reconstitution

Briefly centrifuge the vial before opening. It is recommended to reconstitute the protein in sterile PBS containing 0.1% endotoxin-free recombinant human serum albumin.

 

Stability & Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. In general: 12 months from date of receipt, -20 to -80°C as supplied. 1 month, 2 to 8°C under sterile conditions after reconstitution. 3 months, -20 to -80°C under sterile conditions after reconstitution.

 

Protein Description

Recombinant human SCF expressed in engineered human cells. SCF belongs to the IL-2 protein family. SCF is a 35 to 45 kDa monomeric glycoprotein. SCF is produced by a variety of cells, such as melanocytes, hepatocytes, and bone cells. SCF promotes mast cell development, melanocyte cell survival and proliferation. SCF has been implicated in disease processes characterized by tissue remodeling and fibrosis and acts synergistically in the presence of other cytokines including EPO and GM-CSF.

 

References

Kitamura T, et al. (1989) J. Cell Physiol.140, 323-334.
Ali, S, et al. (2007) Gene 401, 38-45.