Product Application: Recombinant Human FGF Basic (Human Cell Derived)
Primary Application:
- Cell Proliferation and Differentiation: FGF basic is a potent mitogen that stimulates the proliferation and differentiation of various cell types, including fibroblasts, endothelial cells, and neural cells.
- Angiogenesis: It plays a crucial role in angiogenesis, the formation of new blood vessels, which is essential for tissue growth and repair.
- Wound Healing: FGF basic can promote wound healing by stimulating cell proliferation and migration.
- Stem Cell Research: It can be used to maintain the pluripotency of stem cells and induce their differentiation into specific cell types.
Specific Uses:
- Tissue Engineering: FGF basic can be used to enhance tissue regeneration and repair, particularly in wound healing and tissue engineering applications.
- Drug Discovery: It can be used as a target for drug development, particularly in the areas of cancer and cardiovascular disease.
- Basic Research: FGF basic is a valuable tool for studying the mechanisms of cell growth, differentiation, and angiogenesis.
Key Features and Benefits:
- High Purity and Low Endotoxin: Ensures optimal biological activity and minimal off-target effects.
- Recombinant Human FGF Basic: Ensures consistent quality and activity, and avoids potential immunogenicity issues associated with bacterial expression systems.
- Easy to Use: Lyophilized format allows for easy storage and reconstitution.
- Versatile: Can be used in a variety of applications, including research, drug development, and tissue engineering.
In summary, Recombinant Human FGF Basic (Human Cell Derived) offers a superior option for researchers and scientists, providing a more biologically relevant and potentially less immunogenic product for a wide range of applications.
Citations for Recombinant Human FGF basic
Welcome to the documentation download page. Below you'll find important documents related to our products, including Certificates of Analysis (COA), Data Sheets, Material Safety Data Sheets (MSDS), and more. These documents provide essential information for product use, safety, and technical specifications.
Product Specifications
- Expression of Human Proteins in Human Cells
- Extreme low Endotoxin
- High Purity
- Animal Free and Xeno Free
- Tag Free
Source: Human cell derived
Structure: Non-glycosylated monomer
Purity: >95% by SDS-PAGE
Endotoxin Level: <1EU/ug
Molecular Weight:17kDa
Formulation: Lyophilized from a 0.2μm filtered solution in PBS without carrier protein
Activity Assay
The activity was measured by its ability to stimulate the proliferation of 3T3 mouse fibroblast cells.
Reconstitution
Briefly centrifuge the vial before opening. It is recommended to reconstitute the protein in sterile PBS containing 0.1% endotoxin-free recombinant human serum albumin
Stability & Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. In general: 12 months from date of receipt, -20 to -80°C as supplied. 1 month, 2 to 8°C under sterile conditions after reconstitution. 3 months, -20 to -80°C under sterile conditions after reconstitution.
Protein Description
FGF basic is a non-glycosylated heparin binding growth factor that belongs to the fibroblast growth factor family. FGF basic is expressed in the brain, pituitary, kidney, retina, bone, testis, adrenal gland, liver, monocytes, epithelial cells and endothelial cells. The recombinant human FGFbasic is a 17 kDa protein consisting of 154 amino acid residues. FGFbasic signals through FGFR 1b, 1c, 2c, 3c and 4. FGF basic may participate in the production of a variety of pathological conditions resulting from excessive cell proliferation and excessive angiogenesis. FGF basic plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. It also functions as potent mitogen in vitro.
References
Ornitz DM, et al. (1996) J. Biol. Chem. 271, 15292- 15297.
Abraham JA, et al. (1986) Cold Spring Harb. Symp. Quant. Biol. 51, 657-668.
Recombinant Human FGFbasic
- Brand: StemImmune LLC
- Product CAT#: HST-F2-0010 (10ug), HST-F2-0100 (100ug), HST-F2-1000 (1000ug)
- Availability: In Stock
Available Options
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Tags: Growth Factors