Product Application: Recombinant Human IL-7
Primary Application:
- Hematopoiesis: IL-7 is a crucial growth factor that stimulates the proliferation and differentiation of hematopoietic stem cells into lymphoid progenitor cells.
- Immunology: IL-7 plays a role in the development and maintenance of T cells and B cells.
- Stem Cell Research: IL-7 is used to culture and expand T cells for research and therapeutic purposes.
Specific Uses:
- Immunotherapy: IL-7 can be used to enhance immune responses against cancer and viral infections.
- Vaccinology: IL-7 can be used as an adjuvant to enhance the efficacy of vaccines.
- Stem Cell Therapy: IL-7 can be used to expand T cells for adoptive cell therapy.
- Research: IL-7 is widely used in research to study immune cell development and function.
Key Features and Benefits:
- High Purity and Low Endotoxin: Ensures optimal biological activity and minimal off-target effects.
- Recombinant Human IL-7: Guarantees consistent quality and activity.
- Easy to Use: Lyophilized format allows for easy storage and reconstitution.
- Versatile: Can be used in a variety of applications, including research, clinical, and therapeutic settings.
In summery, Recombinant Human IL-7 is a crucial growth factor involved in hematopoiesis, immunology, and stem cell research. It's used in immunotherapy, vaccinology, stem cell therapy, and research to study immune cell development and function.
Citations for Recombinant Human IL-7
Chemical reprogramming of human somatic cells to pluripotent stem cells. Nature (4/13/2022)
Welcome to the documentation download page. Below you'll find important documents related to our products, including Certificates of Analysis (COA), Data Sheets, Material Safety Data Sheets (MSDS), and more. These documents provide essential information for product use, safety, and technical specifications.
Product Specifications
- Expression of Human Proteins in Human Cells
- Extreme low Endotoxin
- High Purity
- Animal Free and Xeno Free
- Tag Free
Source: Human cells derived
Structure: Glycosylated monomer
Purity: >95% by SDS-PAGE
Endotoxin Level: <0.5EU/ug
Molecular Weight: 9-30kDa
Formulation: Lyophilized from a 0.2μm filtered solution in PBS without carrier protein
Activity Assay
The activity was measured by its ability to stimulate the proliferation of murine 2E8 cells.
Reconstitution
Briefly centrifuge the vial before opening. It is recommended to reconstitute the protein in sterile PBS containing 0.1% endotoxin-free recombinant human serum albumin.
Stability & Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. In general: 12 months from date of receipt, -20 to -80°C as supplied. 1 month, 2 to 8°C under sterile conditions after reconstitution. 3 months, -20 to -80°C under sterile conditions after reconstitution.
Protein Description
IL-7 is secreted by stromal cells in the bone marrow and thymus and belong to a hematopoietic growth factors. IL-7 stimulates the differentiation of multipotent (pluripotent) hematopoietic stem cells into lymphoid progenitor cells. IL-7 could also be beneficial in improving immune recovery after allogenic stem cell transplant. Recombinant human is 9, 25, and 30 kDa, monomer, glycosylated protein under reduced condition.
References
Snyder KM, et al (July 2006). Leuk. Lymphoma 47 (7): 1222-8
Heufler C, T et al. (September 1993). J. Exp. Med. 178 (3): 1109-14.
Recombinant Human IL-7
- Brand: StemImmune LLC
- Product CAT#: HCT-I7-0010 (10ug), HCT-I7-0100 (100ug), HCT-I7-1000 (1000ug)
- Availability: In Stock
Available Options
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Tags: Interleukins