Humanized Cytokines

Human proteins processed in vivo require multi-step posttranslational modifications, such as folding, glycosylation, and other modifications. An example of this is the processing of the TGF-beta superfamily. Furin, a protein in humans, cleaves specific sections and activates TGF-beta superfamily proteins. Non-human cells, such as E. coli, lack the necessary processing machinery for these modifications. Human cells, on the other hand, possess the machinery to produce correct disulfide bonds, glycosylation, and proper protein structures.

 

Cell type

Human Cell

E. Coli Cell

Cell Picture

ER

With

Without

Golgi

With

Without

Mitochondria

With

Without

Lysosome

With

With

Ribosome

With

Without


Recombinant Human Activin A

Recombinant Human Activin A

Product Specifications Expression of Human Proteins in Human Cells Extreme low Endotoxin H..

$0.00

Recombinant Human BMP-4

Recombinant Human BMP-4

Product Specifications Expression of Human Proteins in Human Cells Extreme low Endo..

$0.00

Recombinant Human TGF-β1

Recombinant Human TGF-β1

Product Specifications Expression of Human Proteins in Human Cells Extreme low Endotoxin H..

$0.00

Recombinant Human BMP-2

Recombinant Human BMP-2

Product Specifications Expression of Human Proteins in Human Cells Extreme low Endotoxin H..

$0.00

Recombinant Human TGF-β2

Recombinant Human TGF-β2

Product Specifications Expression of Human Proteins in Human Cells Extreme low Endotoxin H..

$0.00

Recombinant Human BMP-7

Recombinant Human BMP-7

Product Specifications Expression of Human Proteins in Human Cells Extreme low Endotoxin H..

$0.00

Heat Stable Recombinant Human FGFbasic

Heat Stable Recombinant Human FGFbasic

Product Specifications Expression of Human Proteins in Human Cells Extreme low Endotoxin H..

$0.00

Recombinant Human TGF-β3

Recombinant Human TGF-β3

Product Specifications Expression of Human Proteins in Human Cells Extreme low Endotoxin H..

$0.00

Recombinant Human Noggin

Recombinant Human Noggin

Product Specifications Expression of Human Proteins in Human Cells Extreme low Endotoxin H..

$0.00

Recombinant Human FGF-7 (KGF)

Recombinant Human FGF-7 (KGF)

Product Specifications Expression of Human Proteins in Human Cells Extreme low Endotoxin H..

$0.00

Recombinant Human IL-3

Recombinant Human IL-3

  Product Specifications Expression of Human Proteins in Human Cells Extreme low Endot..

$0.00

Recombinant Human IL-6

Recombinant Human IL-6

Product Specifications Expression of Human Proteins in Human Cells Extreme low Endotoxin H..

$0.00

Recombinant Human FLT3-Ligand

Recombinant Human FLT3-Ligand

Product Specifications Expression of Human Proteins in Human Cells Extreme low Endotoxin H..

$0.00

Recombinant Human GM-CSF

Recombinant Human GM-CSF

Product Specifications Expression of Human Proteins in Human Cells Extreme low Endotoxin H..

$0.00

Recombinant Human G-CSF

Recombinant Human G-CSF

Product Specifications Expression of Human Proteins in Human Cells Extreme low Endotoxin H..

$0.00

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