Product Application: Recombinant Human IFN-γ (E. coli Derived)
Primary Application:
- Immunomodulation: IFN-γ is a potent immunomodulatory cytokine that activates immune cells and enhances their ability to fight infections.
- Antiviral Activity: It has strong antiviral properties and is used to treat viral infections, including hepatitis B and C.
- Cancer Therapy: IFN-γ can be used to treat certain types of cancer, such as renal cell carcinoma and melanoma.
- Autoimmune Diseases: It can be used to treat autoimmune diseases, such as multiple sclerosis.
Specific Uses:
- Viral Infections: IFN-γ can be used to treat viral infections, including hepatitis B and C.
- Cancer Therapy: It is used in the treatment of various cancers, such as renal cell carcinoma and melanoma.
- Immunotherapy: IFN-γ can be used to enhance the effectiveness of immunotherapy treatments.
- Research: IFN-γ is widely used in research to study the immune response and cell signaling pathways.
Key Features and Benefits:
- High Purity and Low Endotoxin: Ensures optimal biological activity and minimal side effects.
- Recombinant Human IFN-γ: Guarantees consistent quality and activity.
- Easy to Use: Lyophilized format allows for easy storage and reconstitution.
- Versatile: Can be used in a variety of applications, including research, Pre-clinical, and therapeutic settings.
In summery: Recombinant Human IFN-γ is a potent immunomodulatory cytokine with diverse applications in research, pre-clinical studies, and therapeutic interventions. It's particularly effective in modulating immune responses, combating viral infections, and treating certain cancers. High purity, low endotoxin, and recombinant origin ensure quality and activity. The lyophilized format offers convenience.
Welcome to the documentation download page. Below you'll find important documents related to our products, including Certificates of Analysis (COA), Data Sheets, Material Safety Data Sheets (MSDS), and more. These documents provide essential information for product use, safety, and technical specifications.
Source: E. coli derived
Structure: Noncovalently linked homodimer
Purity: >95% by SDS-PAGE
Endotoxin Level: <1EU/ug
Molecular Weight: 16.8 kDa
Formulation: Lyophilized from a 0.2μm filtered solution in PBS without carrier protein
Activity Assay
Determined by its ability to induce apoptosis in HeLa cells.
Reconstitution
Briefly centrifuge the vial before opening. It is recommended to reconstitute the protein in sterile PBS containing 0.1% endotoxin-free recombinant human serum albumin.
Stability & Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. In general: 12 months from date of receipt, -20 to -80°C as supplied. 1 month, 2 to 8°C under sterile conditions after reconstitution. 3 months, -20 to -80°C under sterile conditions after reconstitution.
Protein Description
IFNγ is an acid-labile interferon produced by Th1, cytotoxic T cells, NKT cells and NK cells. Interferon gamma (IFNγ) is a dimerized soluble cytokine that is the type II class of interferons.IFNγ signaling in antigen-presenting cells, and antigenrecognizing B and T lymphocytes, regulates the antigen-specific phases of the immune response. IFNγ is critical for innate and adaptive immunity against viral, protozoal, bacterial infections. It also exhibits antiviral, antiproliferative, and apoptotic effects. IFNγ is particularly suitable for human CIK activation along with IL-2.
References
Gray PW, et al. (1982) Nature 298 (5877): 859-63.Jiang J, et al. (2013) J Transl Med 11:83.
Lin FC, et al. (2014) Cytokine Growth Factor Rev 25(4):369-76.
Recombinant Human IFNγ
- Brand: StemImmune LLC
- Product CAT#: EST-IFg-0010 (10ug), EST-IFg-0100 (100ug), EST-IFg-1000 (1000ug)
- Availability: In Stock
Available Options
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