Product Application: Recombinant Human IL-1β
Primary Application:
- Inflammation: IL-1β is a potent pro-inflammatory cytokine that plays a crucial role in the inflammatory response.
- Immune Response: It stimulates the immune response by activating various immune cells, including T cells and macrophages.
- Tissue Repair: IL-1β is involved in tissue repair and regeneration processes.
Specific Uses:
- Research: IL-1β is widely used in research to study inflammation, immune response, and cell signaling pathways.
- Drug Discovery: It can be used as a target for drug development to treat inflammatory diseases.
- Biomedical Research: IL-1β is used in various biomedical research applications, such as studying the pathogenesis of inflammatory diseases.
Key Features and Benefits:
- High Purity and Low Endotoxin: Ensures optimal biological activity and minimal off-target effects.
- Recombinant Human IL-1β: Guarantees consistent quality and activity.
- Easy to Use: Lyophilized format allows for easy storage and reconstitution.
- Versatile: Can be used in a variety of applications, including research, drug development, and diagnostic assays.
In summery, Recombinant Human IL-1β is a potent pro-inflammatory cytokine involved in inflammation, immune response, and tissue repair. It's used in research, drug discovery, and biomedical research to study inflammatory processes, immune responses, and cell signaling pathways.
Citations for Recombinant Human IL-1β
Welcome to the documentation download page. Below you'll find important documents related to our products, including Certificates of Analysis (COA), Data Sheets, Material Safety Data Sheets (MSDS), and more. These documents provide essential information for product use, safety, and technical specifications.
Product Specifications
- Expression of Human Proteins in Human Cells
- Extreme low Endotoxin
- High Purity
- Animal Free and Xeno Free
- Tag Free
Source: Human cells derived
Structure: Glycosylated heterodimer
Purity: >95% by SDS-PAGE
Endotoxin Level: <0.5EU/ug
Molecular Weight: 18-25kDa
Formulation: Lyophilized from a 0.2μm filtered solution in PBS without carrier protein
Activity Assay
The activity was measured by its ability to stimulate the proliferation of the proliferation of mouse D10S cells.
Reconstitution
Briefly centrifuge the vial before opening. It is recommended to reconstitute the protein in sterile PBS containing 0.1% endotoxin-free recombinant human serum albumin.
Stability & Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. In general: 12 months from date of receipt, -20 to -80°C as supplied. 1 month, 2 to 8°C under sterile conditions after reconstitution. 3 months, -20 to -80°C under sterile conditions after reconstitution.
Protein Description
IL-1 includes two pleiotropic cytokines, IL- 1α and IL-1β. Both IL-1α and IL-1β bind to the same receptor and have similar, if not identical, biological properties. IL-1β is a proinflammatory cytokine produced in a variety of cells, including monocytes, tissue macrophages, keratinocytes, and other epithelial cells. These cytokines have a broad range of activities including the stimulation of thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity.
References
Bensi G, et al. (1987) Gene 52,95-101.
Van Damme J, et al. (1985) Nature 314,266-268.
Kornman KS (2006) Am. J. Clin. Nutr. 83, 475S.
Recombinant Human IL-1β
- Brand: StemImmune LLC
- Product CAT#: HCT-IB1-0010 (10ug), HCT-IB1-0100 (100ug), HCT-IB1-1000 (1000ug)
- Availability: In Stock
Available Options
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Tags: Interleukins