Product Application: Recombinant Human FGF-4
Primary Application:
- Stem Cell Research: FGF-4 is a crucial growth factor for maintaining the pluripotency of embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs).
- Tissue Engineering: It can be used to promote cell proliferation and differentiation in tissue engineering applications, such as skin regeneration and wound healing.
- Developmental Biology: FGF-4 plays a critical role in embryonic development, particularly in limb and heart development.
- Cancer Research: FGF-4 has been implicated in tumor growth and metastasis, and it can be used as a target for cancer therapy.
Specific Uses:
- Stem Cell Culture: FGF-4 is essential for the culture and maintenance of stem cells.
- Tissue Regeneration: It can be used to promote tissue regeneration in various applications, such as skin grafts and nerve repair.
- Drug Discovery: FGF-4 can be used as a target for drug development, particularly in the areas of cancer and regenerative medicine.
Key Features and Benefits:
- High Purity and Low Endotoxin: Ensures optimal biological activity and minimal off-target effects.
- Recombinant Human FGF-4: Ensures consistent quality and activity.
- Easy to Use: Lyophilized format allows for easy storage and reconstitution.
- Versatile: Can be used in a variety of applications, including stem cell research, tissue engineering, and drug discovery.
Summery: Recombinant Human FGF-4 is a valuable tool for researchers and scientists working in the fields of stem cell biology, tissue engineering, and developmental biology. It offers a versatile and effective way to manipulate cell growth and differentiation.
Welcome to the documentation download page. Below you'll find important documents related to our products, including Certificates of Analysis (COA), Data Sheets, Material Safety Data Sheets (MSDS), and more. These documents provide essential information for product use, safety, and technical specifications.
Product Specifications
- Expression of Human Proteins in Human Cells
- Extreme low Endotoxin
- High Purity
- Animal Free and Xeno Free
- Tag Free
Structure: Glycosylated homodimer
Purity: >95% by SDS-PAGE
Endotoxin Level: <0.5EU/ug
Molecular Weight: 17-27kDa
Formulation: Lyophilized from a 0.2μm filtered solution in PBS without carrier protein
Activity Assay
The activity was measured by its ability to stimulate the proliferation of 3T3 mouse fibroblast cells.
Reconstitution
Briefly centrifuge the vial before opening. It is recommended to reconstitute the protein in sterile PBS containing 0.1% endotoxin-free recombinant human serum albumin.
Stability & Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. In general: 12 months from date of receipt, -20 to -80°C as supplied. 1 month, 2 to 8°C under sterile conditions after reconstitution. 3 months, -20 to -80°C under sterile conditions after reconstitution.
Protein Description
FGF-4 is a heparin binding growth factor that belongs to the fibroblast growth factor family. FGF- 4 is proposed to play a physiologically relevant role in the regulation of embryonic development, cell proliferation, and cell differentiation. It is required for normal limb and cardiac valve development during embryogenesis.
References
Mayshar Y, et al. (2008) Stem Cells 26,767-774.
Ornitz DM, et al. (1996) J. Biol. Chem. 271, 15292-15297.
Hebert JM, et al. (1990) Dev. Biol. 138,454.
Recombinant Human FGF-4
- Brand: StemImmune LLC
- Product CAT#: HST-F4-0010 (10ug), HST-F4-0100 (100ug), HST-F4-1000 (1000ug)
- Availability: In Stock
Available Options
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Tags: Growth Factors