• Recombinant Human FGF-7 (KGF)

Product Application: Recombinant Human FGF-7 (KGF)

Primary Application:

  • Epithelial Cell Growth and Differentiation: FGF-7 is a potent growth factor that stimulates the proliferation and differentiation of epithelial cells, particularly keratinocytes.
  • Wound Healing: It plays a crucial role in wound healing by promoting cell migration and proliferation.
  • Tissue Engineering: FGF-7 can be used to enhance tissue regeneration and repair, especially in epithelial tissues.
  • Cancer Research: FGF-7 has been implicated in tumor growth and metastasis, and it can be used as a target for cancer therapy.

Specific Uses:

  • Skin Regeneration: FGF-7 can be used in topical treatments to promote skin regeneration and wound healing.
  • Oral Mucosal Healing: It can be used to accelerate the healing of oral ulcers and wounds.
  • Drug Delivery: FGF-7 can be used to enhance the delivery of drugs to target tissues.
  • Research: FGF-7 is used in research to study epithelial cell growth, differentiation, and signal transduction pathways.

Key Features and Benefits:

  • High Purity and Low Endotoxin: Ensures optimal biological activity and minimal off-target effects.
  • Recombinant Human FGF-7: Ensures consistent quality and activity.
  • Easy to Use: Lyophilized format allows for easy storage and reconstitution.
  • Versatile: Can be used in a variety of applications, including research, drug development, and cosmetics.

In summery, Recombinant Human FGF-7 (KGF) is a valuable tool for researchers and scientists working in the fields of cell biology, tissue engineering, regenerative medicine, and drug development. It offers a versatile and effective way to stimulate epithelial cell growth and differentiation.

Welcome to the documentation download page. Below you'll find important documents related to our products, including Certificates of Analysis (COA), Data Sheets, Material Safety Data Sheets (MSDS), and more. These documents provide essential information for product use, safety, and technical specifications.

 

Source: E.coli derived
Structure: Monomer
Purity: >95% by SDS-PAGE
Endotoxin Level: <1EU/ug
Molecular Weight: 19kDa
Formulation: Lyophilized from a 0.2μm filtered solution in PBS without carrier protein

Activity Assay

The activity was measured by its ability to stimulate the proliferation of 4MBr-5 cells (monkey epithelial cell line).

Reconstitution

Briefly centrifuge the vial before opening. It is recommended to reconstitute the protein in sterile PBS containing 0.1% endotoxin-free recombinant human serum albumin.

Stability & Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. In general: 12 months from date of receipt, -20 to -80°C as supplied. 1 month, 2 to 8°C under sterile conditions after reconstitution. 3 months, -20 to -80°C under sterile conditions after reconstitution.

Protein Description

FGF­7 (KGF) is a member of the fibroblast growth factor family. FGF-7 is expressed in mesenchymal origin cells. FGF-7 is a mitogen factor specific for epithelial cells and keratinocytes. FGF-7 plays a role in kidney and lung development, as well as in angiogenesis and wound healing. FGF­7 also plays an important role in the regulation of embryonic development, cell proliferation and cell differentiation. FGF­7 is possible major paracrine effector of normal epithelial cell proliferation.

References

Finch PW, et al. (1989) Science 245,752-755.
Aaronson SA, et al. (1991) Ann. N. Y. Acad. Sci. 638, 62-77.
Werner S, et al (2007) J. Invest. Dermatol. 127,998.

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Recombinant Human FGF-7 (KGF)

  • Brand: StemImmune LLC
  • Product CAT#: EST-KF-0010 (10ug), EST-KF-0100 (100ug), EST-KF-1000 (1000ug)
  • Availability: In Stock

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Tags: Growth Factors