Product Application: Recombinant Human SCF

Primary Application:

Hematopoiesis: SCF plays a crucial role in hematopoiesis, particularly in the development of hematopoietic stem cells.
Immunology: SCF is involved in the regulation of immune cell development and function.
Tissue Repair: SCF can promote tissue repair and regeneration.

Specific Uses:

Stem Cell Research: SCF is used to culture and expand hematopoietic stem cells.
Cancer Therapy: SCF can be used to stimulate hematopoiesis after chemotherapy or radiation therapy.
Research: SCF is widely used in research to study hematopoiesis, immune cell development, and tissue repair.

Key Features and Benefits:

High Purity and Low Endotoxin: Ensures optimal biological activity and minimal off-target effects.
Recombinant Human SCF: Guarantees consistent quality and activity.
Easy to Use: Lyophilized format allows for easy storage and reconstitution.
Versatile: Can be used in a variety of applications, including research, clinical, and therapeutic settings.

In summery, Recombinant Human SCF is a potent growth factor that plays a crucial role in hematopoiesis, immune cell development, and tissue repair. It's valuable for stem cell research, cancer therapy, and various research applications. High purity, low endotoxin, and recombinant origin ensure quality and activity. The lyophilized format offers convenience.

Citations for Recombinant Human SCF

Welcome to the documentation download page. Below you'll find important documents related to our products, including Certificates of Analysis (COA), Data Sheets, Material Safety Data Sheets (MSDS), and more. These documents provide essential information for product use, safety, and technical specifications.

Product Specifications

Expression of Human Proteins in Human Cells
Extreme low Endotoxin
High Purity
Animal Free and Xeno Free
Tag Free

Source: Human cells derived
Structure: Glycosylated monomer
Purity: >95% by SDS-PAGE
Endotoxin Level: <0.5EU/ug
Molecular Weight: 35-45kDa
Formulation: Lyophilized from a 0.2μm filtered solution in PBS without carrier protein

Activity Assay

The specific activity was determined by the dose- dependent simulation of the proliferation of human TF-1 cells (human erythroleukemic indicator cell line).

Reconstitution

Briefly centrifuge the vial before opening. It is recommended to reconstitute the protein in sterile PBS containing 0.1% endotoxin-free recombinant human serum albumin.

Stability & Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. In general: 12 months from date of receipt, -20 to -80°C as supplied. 1 month, 2 to 8°C under sterile conditions after reconstitution. 3 months, -20 to -80°C under sterile conditions after reconstitution.

Protein Description

Recombinant human SCF expressed in engineered human cells. SCF belongs to the IL-2 protein family. SCF is a 35 to 45 kDa monomeric glycoprotein. SCF is produced by a variety of cells, such as melanocytes, hepatocytes, and bone cells. SCF promotes mast cell development, melanocyte cell survival and proliferation. SCF has been implicated in disease processes characterized by tissue remodeling and fibrosis and acts synergistically in the presence of other cytokines including EPO and GM-CSF.